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ADVERSE REACTIONS TO DRUGS IN ELDERLY WITH CLOPIDOGREL

Two recent articles bearing on the importance of this issue in the elderly:

preevención Recommendations on adverse drug reactions in older people with dementia. J.Gómez-Pavón et al. in English Journal of Geriatrics and Gerontology. 2010, 45 (2) :89-96
The authors, on behalf of the Working Group and Iatrogenic Drugs and Dementia Group of the English Society of Geriatrics and Gerontology and focused on the importance of polypharmacy, give us a series of recommendations for the use of drugs in the patient with dementia, with or without associated behavioral disorders, with an algorithm to manage these symptoms.

In another article, adverse drug events in hospitalized patients in internal medicine. A.Zapatero-Gaviria et al, RevClinEsp.2010.doi: 10.1016/j.rce.2009.12.010 , study 1,567,659 done on diagnoses, coded according to ICD-9 hospital discharge of internal medicine in the hospitals of the national health system, more adverse reactions observed in the elderly, mean age 72'28 and in women . The incidence of adverse reactions in this study is 5'55%, which the authors consider lower than expected by the underreporting of these adverse events in the discharge report.